In vivo tracking the fate of macrophage cells by NIR-II live imaging

Macrophages are the mainstay of the immune system. However, the in vivo temporal and spatial patterns of macrophages is not fully studied, while it has significant implications for investigating the internal mechanism of macrophage response. Particularly, the in vivo Spatial-Temporal pattern of macrophage reflects the overall restoration of inflammation response in the diseased tissue. Thus, in vivo studying the fate of macrophage including kinetics and distribution will deepen understanding the underlying mechanism of inflammation response compared to ex vivo and in vitro. Prof.Jun Chen’group study the in vivo fate of macrophages by tracking the spatial-temporal characterizations of macrophage in different injured soft tissue animal models based on NIR-II imaging.

Prof Jun Chen He is currently the director of laboratory of Sports Medicine Institute of Fudan University, and is the Professor of Huashan Hospital, Fudan University, China. He obtained the doctor degree of biomedical engineering from Shanghai Jiao Tong University in 2013. He moved to Huashan Hospital, Fudan Unversity for two years as a postdoctor, and then leads a multidiscipline research group on biomedical engineering for Sports Medicine. Until now, He has had published more than 40 articles in high impact factor international journals such as Adv. Sci, Chem. Mater., Biomaterials, Small, Nanoscale, Nano Res.and Chem. Commun., etc, and also has 19 Chinese patents of invention. His research interests including immune science, molecular imaging and multifunctional advance materials for biomedical application.

Wednesday, April 24th, 2024 from 11:00 AM to 12:00 PM